Technical basics

Neutral-cure vs acetoxy silicone: what's the difference?

Acetoxy silicone smells of vinegar and can attack some metals and stone. Neutral cure doesn't. Here's which one to use where.

Two silicone joint samples beside glass, coated metal and masonry substrate pieces in a materials workspace
Cure family changes the first compatibility questions, but the actual product and two bonding surfaces still decide the result.

Short answer

Acetoxy silicone releases acetic acid as it cures, so it smells of vinegar and can attack some metals, natural stone and uPVC. Neutral-cure silicone releases no acid, so it's the safer choice on mixed or sensitive surfaces. In our range, MP and 802 are acetoxy; AF and N are neutral cure.

Both types cure by reacting with moisture in the air. The difference is what they give off while they do it, and that decides which surfaces they can go on.

Acetoxy: fast, strong on glass, limited elsewhere

Acetoxy silicone bonds very well to glass, glazed ceramic, aluminium and other non-porous surfaces, and it cures quickly. The acid it releases is the catch.

Pereseal 802 is our acetoxy glazing silicone. It is certified to ASTM C920 Class 25, with ±25% movement, for glass and metal glazing, curtain wall, skylights and sheet metal. It is not for marble, quartzite or natural stone, not for structural glazing, and the acid may corrode susceptible metals.

Pereseal MP is our general-purpose acetoxy silicone. It skins in about 7 minutes. It isn't for uPVC, and copper and lead may be attacked.

Glass, ceramic, coated aluminium, masonry and plastic samples arranged for silicone compatibility review
Name both surfaces first. That decides the cure type.

Neutral cure: the safer choice on mixed surfaces

Neutral-cure silicone releases no acid. It's non-corrosive to metals and alkaline surfaces such as concrete, and it has only a mild smell, which matters in an occupied room.

Pereseal N is our weatherproof neutral silicone for windows, masonry, concrete, stone, aluminium, most plastics and roofing joints. It takes ±30% movement. Pereseal AF is the neutral-cure silicone for bathrooms and kitchens, with a fungicide added.

Neutral isn't universal either. The AF and N data sheets exclude paint coatings, copper, and polycarbonate or acrylic sheet under tension.

The smell

The vinegar smell of acetoxy silicone is strongest while it cures and fades once it has cured. In a small bathroom or a closed room, ventilate while you work, or use a neutral-cure product. Smell tells you the cure type, not the quality: a sharp smell doesn't mean a stronger seal.

Choosing between them

Start with the two surfaces. If either one is natural stone, uPVC, copper, lead or a sensitive metal, use neutral cure. If both are glass, glazed tile or aluminium, acetoxy works well and cures fast. Then pick for the job: weather, wet area, glazing or general sealing. For the wider choice between sealant families, see acrylic vs silicone.

Which Pereseal silicone

Glass and aluminium glazing, skylights, sheet metal

Pereseal 802, acetoxy, ASTM C920 Class 25.

General sealing on glass, tile and other non-porous surfaces

Pereseal MP, acetoxy. Not for uPVC.

Windows, uPVC, concrete, stone, exterior joints

Pereseal N, neutral cure, ±30% movement.

Baths, showers, basins and sinks

Pereseal AF, neutral cure with fungicide.

Not sure which silicone?

Tell us the two surfaces and whether the joint is inside, outside or in a wet area. We'll tell you which Pereseal to use.

Ask us

Documents

Technical data sheetEN16 Sept 2026

Pereseal AF TDS 2026

Technical data sheet for Pereseal AF anti-fungal neutral silicone sealant.

Technical data sheetEN16 Sept 2026

Pereseal N Clear TDS 2026

Technical data sheet for the clear Pereseal N neutral silicone sealant.

Technical data sheetEN16 Sept 2026

Pereseal N Black, White and Grey TDS 2026

Technical data sheet for black, white and grey Pereseal N neutral silicone sealant.

Technical data sheetEN16 Sept 2026

Pereseal 802 TDS 2026

Technical data sheet for Pereseal 802 acetoxy silicone sealant.

Technical data sheetEN01 Jan 2025

Pereseal MP TDS 2025

Technical datasheet for Pereseal MP multi-purpose silicone sealant.

Products in this guide

Pereseal N Weatherproof Neutral Seal Silicone cartridge
Silicone sealant

Pereseal N Weatherproof Neutral Seal Silicone

Neutral-cure silicone for windows, doors, façades and roofs. Low odour, non-corrosive to metals, and takes up to ±30% joint movement.

Product details
Pereseal AF Anti-Fungal Bathroom & Kitchen Silicone Sealant cartridge
Silicone sealant

Pereseal AF Anti-Fungal Bathroom & Kitchen Silicone Sealant

Anti-fungal neutral-cure silicone for showers, baths, basins, sinks and kitchen worktops. Made for Singapore's heat and humidity.

Product details
Pereseal 802 High Performance Silicone Sealant cartridge
Silicone sealant

Pereseal 802 High Performance Silicone Sealant

Acetoxy silicone for glazing, curtain walls, glass and metal. Certified to ASTM C920 Class 25, with up to ±25% joint movement.

Product details
Pereseal MP Multi-Purpose Silicone Sealant cartridge
Silicone sealant

Pereseal MP Multi-Purpose Silicone Sealant

Everyday acetoxy silicone for construction joints, glazing top seals, tiles, ducting, signs and woodwork. Skins in 7 minutes.

Product details

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